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Gender differences in indian subjects with vascular dementia

Author: 
Mina Chandra and Kuljeet Singh Anand
Subject Area: 
Health Sciences
Abstract: 

Background: Gender differences in Indian subjects with Vascular Dementia have not been studied systematically. Materials and Methods: Subjects with Vascular Dementia presenting to a tertiary care hospital over a period of 16 months were assessed for socio demographic factors, dementia severity using Clinical Dementia Rating (CDR) Scale and for the presence of four vascular disease factors namely Hypertension, Diabetes, Dyslipidaemia and Ischemic Heart Disease. Data was analysed using SPSS version 17. Results: The 159 subjects (M: F = 54.7: 45.3 % p = 0.27) of Vascular Dementia (Mild: Moderate: Severe Dementia = 39.7%, 38.4% and 21.9%) had a mean age of 69.35 (±7.51) years and a mean education of 11.34 (± 3.76) years with females being less educated (p=0.000). More four- fifths of subjects had multiple vascular disease risk factors. The female subjects had a similar severity level of dementia (p=0.401) and vascular disease burden (p= 0.543) despite being significantly younger (p= 0.002). Conclusion: Female subjects of Vascular Dementia were significantly younger than male counterparts despite having a similar vascular risk profile as the male subjects though lower educational levels in females may have also contributed to the cognitive decline.

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