The metabolic fates of C, H, O atoms contained in food molecules in the full 9 stepped cycle of electron and proton conductance inside the human body

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Author: 
Ambaga, M.
Subject Area: 
Health Sciences
Abstract: 

By us established that final conversion, metabolic fates of separate three atoms as C, H, O contained in any forms of foods - donators as carbohydrate, fatty acids, aminoacids occured in the full 9 stepped cycle of electron and proton conductance inside the human body as follows: Metabolic fates of C, O atoms in the full 9 stepped cycle of electron and proton conductance inside the human body: a. C, O atoms contained in food molecules through the 1-th stage and 2-th stage of the full 9 stepped cycle of electron and proton conductance inside the human body have been transferred and converted to CO2 i.e.in these stages acetyl residues of acetyl - CoA and pyruvate, also succinyl - CoA, fumarate, pyruvate, acetyl - CoA, alpha - ketoacids as 7 intermediates of Krebs cycle after oxidative deamination of aminoacids converted to CO2. Metabolic fates of H atoms - first variant in case of free protons in the full 9 stepped cycle of electron and proton conductance inside the human body: a. H atoms contained in food molecules through the 1-th stage as release of proton, electrons from food substrates under the undirect action of oxygen released from membrane surroundings of erythrocyte in the 9-th stage converted to NADH, FADH2. b. b.After these stages of conversion of H atoms contained in food molecules to NADH, FADH2 have been started the next stages of conductance of free protons, including the 5-th stage- as translocation of proton to intermembrane space of mitochondria without accompanying electro, the 6-th stage as creation of proton gradient in the intermembrane space of mitochondria and following transfer of proton to matrix through ATP synthase, the 7-th stage as formation of metabolic water in the mitochondrian matrix by protonation of molecular oxygen by matrix proton, the 8-th stage as diffusion of proton from mitochondrial matrix of all cells and metabolic water formed during protonation of molecular oxygen by matrix proton entered through plasma membrane of red blood cells with participation of aquaporin protein channels, also the 9-th stage - metabolic water entered to red blood cells reacts with CO2 formed in the 2-th stage by formation H2CO3, which is followed by reaction as H2CO3=H+HCO3 and released during this stage free proton promotes the release of oxygen from hemoglobin, i.e. occurred the meeting of CO2 formed in the 2-stage with metabolic water formed in the 7- th stage of the full 9 stepped cycle of electron and proton conductance inside red blood cells. Metabolicfates of H atoms - second variant in case of free electrons in the full 9 stepped cycle of electron and proton conductance inside the human body: a. 4-th stage of the full 9 stepped cycle of electron and proton conductance inside the human body as transfer of electron to cytochrom C and to molecular oxygen without accompanying proton, formation of activated oxygen and 7-th stage as formation of metabolic water in the mitochondrian matrix in the form of oxidation of proton by activated oxygens after obtaining electrons from cytochrom C i.e.protonation of molecular oxygen by matrix proton.

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