CALL FOR PAPERS

Author Information

CERTIFICATE

IMPACT FACTOR 2019

Subject Area

Life Sciences / Biology
Architecture / Building Management
Asian Studies
Business & Management
Chemistry
Computer Science
Economics & Finance
Engineering / Acoustics
Environmental Science
Agricultural Sciences
Pharmaceutical Sciences
General Sciences
Materials Science
Mathematics
Medicine
Nanotechnology & Nanoscience
Nonlinear Science
Chaos & Dynamical Systems
Physics
Social Sciences & Humanities

Why Us? >>

Open Access
Peer Reviewed
Rapid Publication
Life time hosting
Free promotion service
Free indexing service
More citations
Search engine friendly

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

Anxiolytic effects of hydroalcohol extract of feronia limonia (wood apple) fruit in mice model of anxiety

Author:

Ilaiyaraja, N. and Farhath Khanum

Subject Area:

Life Sciences

Abstract:

The anxiolytic effect of hydroalcohol extract of Feronia limonia (HEF) was investigated in the present study. The extract was orally administered to the Balb/C mice for a period of 7 days at the graded dose of 50, 100 and 200 mg/kg, bd.wt. Mice treated with 100 and 200 mg/kg bd.wt extract, significantly increased the time spent by the mice in open arm in elevated plus maze test (EPM), increased the square crossing in open field test (OFT) and increased the numbers of punished lick and shocks received in Vogels conflict test (VCT). Treatment with HEF also reduced the corticosterone levels in plasma, and GABA in brain tissues of mice. Over all the peak anxiolytic effects was obtained at the dose of 100 mg/kg bd.wt in mice. Thus, the present findings suggest the use of FLH as a potential herbal anxiolytic agent.

PDF file: