Introduction: prostate cancer is the commonest cancer in elderly males. It has growing incidence with late stage incurable presentations. Screening andearly detection is the main strategy to compact this disease. Males knowledge and attitude is mandatory to practice screening. The aim of this study is to assess males knowledge, attitude and practice about screening and early detection of prostate cancer via prostate specific antigen (PSA). Materials and Method: This is descriptive, community based cross sectional study. 100 males were recruited in East nile locality in Khartoum state on household basis. 45 years old or more married males were invited to participate. Questionnaire was used to collect data on different variables to assess knowledge, attitude and practice. Results: Knowledge about Ca. prostate nature, symptoms and availability of screening tests was poor. Main source of knowledge was community itself. Attitude about risk and need for screening was good, but very poor screening practice was reported. Conclusion: poor knowledge, fair attitude and very poor practice were found among studied males. Health care providers were the least source of information. Raising awareness about prostate cancer, its risks and necessity of screening and early detection is a shared responsibility between decision makers and health care providers.
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