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The clinical and functional features of drugresistant pulmonary tuberculosis inpatients withchronic obstructive pulmonary disease

Author: 
Jeyhun M. Ismayilzada, Rafiq I. Bayramov, Urfana B. Nagiyeva and Rena I. Hamzayeva
Subject Area: 
Health Sciences
Abstract: 

Objectives: The present study reports the clinical and functional features of the current of drug-resistant pulmonary tuberculosis (TB) in patients withchronic obstructive pulmonary disease(COPD). Material and Methods: The present study reports the 180 patients who were examined in therapeutic departments of Tuberculosis Hospital No. 4 in Baku, which is the base of the Phthisiatry Department of the Azerbaijan Medical University from January 2013 to December 2017. Results: Among the examined were 33 women and 147 men aged 41 to 69 years. 110 patients (61%) had a widespread process in the lung, destructive changes were found in 126 (70%) patients. All patients were divided into two groups: the first group - 119 patients who had obstructive ventilation disorders in their pulmonary function test study, the 2nd group was formed from 71 patients with unchanged functional indices. Among the examined were 33 women and 147 men aged 41 to 69 years. 110 patients (61%) had a widespread process in the lung, destructive changes were found in 126 (70%) patients. Multidrug-resistant form was found in 36.1% of patients of the 1st and 20.5% in the 2nd group. The results of examination and treatment of patients with COPD testified to the severity and slow regress of clinical and radiological manifestations of the disease, the long-term preservation of bronchial patency disorders. All this led to the advisability of developing a basic of treatment program for patients with TB with COPD. Conclusion: The results obtained indicate a negative effect of bronchial obstruction on the tuberculosis process, which led to the development of a basic treatment program combining different methods for eliminating the causes of bronchial obstruction: adequate etiotropic chemotherapy, exposure to pathogenic agents, modern regimens of bronchodilator therapy, and smoking control.

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