
Aims and Objectives: To compare and evaluate the time of onset, profoundness, duration of anesthesia and postoperative complications of Articaine and Lignocaine. Materials and Methods: The study group consists total of 90 patients divided into two groups of 45 each undergone double blind study conducted with Articaine and Lignocaine with surgical removal of impacted mandibular 3rd molars. Clinical parameters like onset of anesthesia, duration of anesthesia, Pain experience and post operative complications were analysed. Results: Onset of anesthesia was (3 to 6 minutes) with mean 4.64 minutes for Articaine and 4.3 minutes for lignocaine. Mean duration of Anesthesia is 390.67 minutes for Articaine and 368 minutes for Lignocaine. Pain (evaluated withVAS scale) during anesthesia is not much significant statistically (Mean value - 2.00). There is also no statistical difference between the two groups (mean value 2.00) for pain during procedure. Paraesthesia was reported in Lignocaine group which resolves itself in due course of time. Conclusion: From the result of our study we can conclude that the onset of action Articaine solution is similar to Lignocaine. 4% Articaine has longer duration of action than 2% Lignocaine. The efficacy of 4% Articaine based on VAS (Visual analog scale) is similar to 2% Lignocaine indicating that Articaine has provided adequate analgesia. Articaine can be used in minor oral surgical procedures like impaction and dentoalveolar surgery.