The kidneys are important organs responsible for filtration, reabsorption and excretion of waste from the body. Renal failure (RF) is mainly determined by a decrease in glomerular filtration rate (GFR); the rate at which blood is filtered in the glomeruli of the kidneys. The decrease of filtration rate is detected by a decrease in or absence of urine production or determination of waste products (creatinine or urea) in the blood. Hematuria (blood loss in the urine) and proteinuria (protein loss in the urine) may be noted in relation to this failure. This study was aimed to compare the occurrence of renal failure among Sudanes people. Eighty patients with renal failure (RF) registered at hospitals in Khartoum State agreed to participate in this study between April - May / 2015. Data was collected from each patient using a specific questionnaire designed for this purpose. Results: revealed that the high percentage of RF was among men (62.5%) compared to 37.5% among females. Moreover, 40% of these patients were found to smoke cigarettes. Regarding family history, 35% of those having high percentage of RF had a family history while 65% without family history. Also of these patients 65% were reported suffering from chronic diseases before RF onset and 35% did not show any sign of disease before it. The chronic diseases included hypertension (58%), diabetes mellitus (30.7%) and heart disease (3.7 %%). In the meantime, 5% of those reported with renal failure was observed to be susceptible to other diseases. Conclusion: The study concluded that chronic disease was found to be main causes of RF and the disease was higher among officials and that a high percentage of it was reported among males and most of them without family history and non -smokers
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