In the last few years, progress in the biomedical evaluation of athletes has caused scientists to consider numerous factors that can be modified by intense physical activity, and at the same time influence in an important way the sportsmen's power output. An increasing emphasis has been placed on the role of macro and trace metals in human health and disease. The aim of the present study was to compare two macroelements Mg and P and the trace elements As, B, Cs, Li, Mg, P, Rb, Sn and Sr in urine samples in middle distance runners with the corresponding levels in referent sedentary subjects matched by age, sex, and geographic area. Twenty-one Spanish national middle distance runners were recruited before the start of their training period. Male students from the Sport Sciences Faculty of Extremadura University, who had not been regularly or systematically performing physical exercise volunteered for this study and constituted the control group. Mg, P, As, B, Cs, Li, Rb, Sr and Sn analysis of urine was performed by ICP-MS. Element analysis concentrations, expressed in μg/g creatinine were: Mg (44,92±36,8vs. 111,30±91,32, p ≤ 0.01); Sn (0,67±0,92 vs. 2,49±3,29, p≤ 0.05), were lower in athletes urine; Cs (5,05 ± 2,65vs. 3,20±1,60,p ≤ 0.01) in athletes urine have higher than the sedentary group. The results showed that there were not statistically differences between urinary concentrations in both groups of As, B, Li, P, Rb and Sr. We can conclude that the population in Extremadurahasnoab normal levels of these metals. But athletes have some modifications to the elimination of some of these metalsthat could be related to possible adaptation stophysical activity.
