
Background: Hepatitis B and C virus infections have become a serious problem of public health and a major cause of morbidity and mortality, particularly in developing countries. Globally, two billion people (about one-third of the world's population) have been infected by Hepatitis B virus (HBV) Objective: To assess the knowledge, attitudes and risk perceptions towards HIV, HBV and HCV infected patients among KKU interns, undergraduate dental and medical students. Methodology: A cross-sectional study was conducted, included clinical levels students and interns in medical and dental collage of King Khalid University. Convenient sampling technique was used to collect the data from all available students and interns who agreed to participate in the study using pretested questionnaire. Results: The study included 536 medical and dental students (268 for each) with ages ranged from 20 to 26 years old and mean age of 23.3 1.3. Female students constituted 67.2% of the sample. About 47% of the students had good level of knowledge regarding HBV infection, 31.2% of them were of good level of knowledge about HCV while 29.9% had good level of knowledge regarding HIV infection. Conclusion and Recommendation: The overall knowledge, attitude and practice of dental and medical students showed satisfactory outcomes. However, female students were more aware than males and medical students were at lower awareness area than dental students.