For this investigation to evaluate on impact of 12 weeks plyometric training to influence the resting heart rate and respiratory rate variables for college level men soccer players. In this investigation twelve men football players who are all studying college level were selected and based on their playing ability, as well who are all participated in district /inter collegiate level football tournament) as a subjects for this study, from Pondicherry university. Since this investigation involved following variables such as resting heart rate and respiratory rate. The subject’s age ranged from 18 – 28 years as per their college/university records. The subjects were underwent plyometric training in the period of 12 weeks. The training was applied for 3 days per week one session 45- 90 minutes programme. The data were collected from experimental group men soccer players such as resting heart rate and respiratory rate variables before and after the plyometric training completion. The collected data were analyzed with paired ‘t’test for evaluating the impact of 12 weeks plyometric training. Results; the selected resting heart rate and respiratory rate variables has been showing positive influence by plyometric training. Hence it is showing that the selected plyometric training is suitable for develop selected physiological variables resting heart rate and respiratory ratevariables.