Evaluation of factors affecting intravenous ct contrast medium kinetics

The aim of this study is to evaluate the effect of patient factors on the intravenous contrast kinetics. The data was obtained from department of Radio Diagnosis & Imaging, Kasturba Hospital, Manipal from 64slice Philips Brilliance scanner (MDCT) multiple detector computed tomography Brilliance. The social demographic profile of the patient (n = 124) revealed that 52.4% (mean age 52.92±14.50) of the patient are male subject and 47.3 % (mean age 52.23±14.7) of the patient are female subject. The result shows that there is a no significant differences in aortic enhancement time within in the group and between the group with the p>0.5 (F= 0.41, p=0.84). In order to evaluate the gender related variations in contrast kinetics, Independent t-test was considered. From our study shows that there is signification different between the male and female research population with the P value = 0.006. The Correlation of arterial enhancement time (AET) with pulse rate (r = -0.52, p = 0.00) and Ejection Fraction (r = -0.016, p = 0.93) shows the result of negative correlation. From our study, the correlation of AET with height (r = 0.45, p=0.00) and weight (r = 0.53, p=0.00) showed positive weak correlation result. In conclusion, excellent vascular enhancement can routinely be obtained for CT scan of the abdomen. The relationship between injection duration, injection rate, and optimal vascular enhancement as shown in our study will remain an important consideration as technology improvements in CT scanning continue and new clinical applications emerge.