Background and Objective: The objective of the study was to identify the predominant oral pathogenic microbes associated with pericoronitis and antibiotic sensitivity of those predominant group of pathogens. Materials and Methods: A total no of 40 patients were selected, subjected to Microbiological evaluation and after performing the antibiotic sensitivity test, proper antibiotic therapy was given. These subjects were divided into 2 groups –Pre antibiotic & Post antibiotic, each group constituted 20 patients. Swab was collected from the depth of the pericoronal pockets for microbiological evaluation and their Antibiotic sensitivity test. Results: The results suggested that, both aerobic and anaerobic bacteria colonized in mixed infections of oral cavity as pericoronitis, but the distinguishing feature between these two groups that after proper antibiotic treatment the percentage of bacterial count (especially the anaerobes) markedly diminished. Conclusion: It was concluded from the results that, Amoxycillin Clavulanate fully encompasses the aerobic microorganisms whereas Metronidazole was particularly effective against the anaerobes.
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