
Sialolithiasis is the most common disease of the salivary glands. Sialolithiasis accounts for 30% of salivary diseases. Sialolithiasis most commonly involves the submandibular glands (83-94%) and less frequently the parotid (4-10%) and the sublingual glands (1-7%). Intraductal sialoliths are more common when compared to intraglandular sialoliths. According to the available literature, salivary calculi affecting the parotid gland are usually unilateral and are located in the duct. Their size is smaller than submandibular sialoliths, most of them being less than 1 cm. They rarely measure more than 1.5 cm. The mean size varies from 6 to 9 mm. Giant sialoliths are defined as the sialoliths greater than 1.5 cm. in size. Large intra-glandular sialoliths have been frequently reported but large sialoliths in the salivary ducts have been rarely described. Herewith, we report a case of a giant sialolith in the left parotid duct occurring in a 56 year old female, with the clinical and radiographic presentation and a review of literature.