Impact of age, gender, and co morbidities in cardiopulmonary indicators And dysfunctional ventilator weaning response after coronary Artery bypass graft surgery

About 20% to 40% of patients who have undergone Coronary Artery Bypass Graft Surgery (CBAG) remain intubated 12 hours after surgery due to dysfunctional ventilator weaning response (DVWR). DVWR is associated with increased morbidity and mortality (30% to 43%) following CABG surgery. Literature review revealed that there is an association between gender and preoperative co- morbidities and post-operative hemodynamic alterations. Finding significant antecedence to predict DVWR could help to identify and prevent the complications from DVWR after CABG surgery. The purposes of this secondary analysis were to describe the gender and co morbidity distribution among patients those who developed dysfunctional ventilator weaning response and normal ventilator weaning response( NVWR) after CABG surgery and to determine the differences in the distribution of gender and co morbidity among patients with DVWR and NVWR. Findings of the secondary analysis revealed that gender had significant effects on hemodynamic cardiopulmonary indicators (CPI) such as MAP (p = 0.0012), CO (p < 0.0001), and CI (p < 0.0001) post operatively. From these findings, future studies may be conducted using prospective designs in finding the associations and predictive values of gender, co morbidities and cardiopulmonary indicators in Dysfunctional ventilator weaning response, which may have implications in quality care of patients who undergo CABG surgery.