An overview of the history of Open and Distance Education integration strategies in institutions of repute the world over reveals at least two distinct characteristic features: being fraught with myriad challenges and an outstanding determination and resolve exhibited by the founders to make a success of the project in order to achieve the set goals of ODL. This paper examines the educational management and technical challenges facing integration and implementation of Open and Distance Learning programmes in public universities in Kenya. The paper is based on a study conducted in six of the seven public universities in Kenya, namely Maseno, Moi, Masinde Muliro, Egerton, Kenyatta, Nairobi and Jomo Kenyatta Universities. Data was collected using questionnaires and interview schedules from 20 departmental chairs and practitioners. These respondents were purposefully selected along with 378 students randomly selected from the accessible population. The data was analyzed using Chi-square test of goodness of fit and percentage distribution techniques. The findings indicated that there was inadequacy of trained teaching and technical staff, funds allocation, infrastructure in general, motivation of faculty, student support provision and lack of policy guidelines on ODL crucial issues. The research recommendations included the need for adequate training of human resource personnel, and liaison between the universities and the government and other interested stakeholders to help in infrastructure acquisition.