Introduction: December 2019, in the city of Wuhan, an outbreak of Severe Acute Respiratory Syndrome began. Although the respiratory system is the most affected, experimental studies show involvement of the nervous system. In view of the similarity in the SARS-CoV-2 genome with SARS-CoV and MERS-CoV, and the presence of reports of neuropathies in patients infected with these, the aim of this article is to describe the main evidence regarding the causal relation between COVID -19 and peripheral neuropathies, in addition to possible mechanisms involved in this process. Methodology: This is an integrative literature review, made through articles that discuss the relation between COVID-19 infection and the manifestation of neuropathies. The databases used were: PubMed, LILACS, BIREME, being considered important scientific bases of international scope. Searches were limited to articles from the year 2020, in English and Portuguese. Discussion: It is known that the involvement generated by the coronavirus is diffuse, even acting on the central and peripheral nervous systems. Although there are studies that propose a possible causal relation between the new human coronavirus and the manifestation of Guillain-Barré Syndrome, Miller-Fisher Syndrome, and cranial polyneuropathy, there is no evidence to prove this. Conclusion: The manifestation of neuropathies by patients with COVID-19 has been demonstrated in different studies. Even so, the mechanism responsible for the appearance of these clinical conditions must be better elucidated. Therefore, it is not yet possible to determine whether the relation between COVID-19 infection and presentation of neuropathies is causal or coincidental.