
Ovarian hyperstimulation syndrome (OHSS) is a well recognized iatrogenic complication of assisted conception techniques, which uses pharmacological ovarian stimulation during assisted reproductive technology (ART). However, in most cases OHSS is self-limiting and requires supportive management and monitoring while awaiting resolution. In a minority of women undergoing treatment it can result in life-threatening complications such as thrombo-embolic phenomena and multiple organ dysfunctions. The key principles of OHSS management therefore are early recognition and the prompt assessment and treatment. The recent increase in the usage of ART will inevitably result in a rise in the number of cases of OHSS seen in the emergency department (ED), this will give the emergency physician an important role in expediting and optimizing treatment for these patients. Five cases in their early thirties with a history of nausea, vomiting, breathlessness and bloating after ovarian stimulation were enrolled. Cases were confirmed to be suffering from severe OHSS and received supportive management.