Phosphor is considered among the major pollutants in water environments. Phosphor contamination in surface water and groundwater resources originates mainly from the excessive use of fertilizers and uncontrolled land discharges of untreated wastewater. Discharge of it into the environment causes very health impact. The aim of this study was to investigate the efficiency of Fenton’s advanced oxidation process (H2O2/Fe+2) in phosphor removal from aqueous solutions. This is an experimental study which is carried out in laboratory scale. In this study, effect of the important operational variables including pH, Fe+2 dosage, H2O2 dosage, initial phosphor concentration and contact time were evaluated on the phosphate removal from Aqueous Solution by Fenton has been investigated. The results showed that this method has the ability to remove phosphor from aqueous solutions to less than standard level WHO (≤1 mg/l). pH, ratio H2O2/Fe+2 and contact time have direct effect and initial phosphor concentration has reverse effect of phosphor removal. The results showed that the Fenton process, can reach respectively 97% phosphor removal. So that optimum condition of the phosphor removal is in the ratio H2O2 / Fe2+ dosage= 2200 /1000 mg/l, contact time of 60 min, pH=3.5 in initial phosphor concentration in 100 mg/L. Statistical test showed that the mean concentration in the before and after doing all process variables, there were significant differences (P≤0.05). As the results showed, the efficient removal of phosphate using Fenton process is desirable in the water treatment and pollution control.