
Aim of study: To study perinatal transmission in PLWH delivered in last five years at C. U. SHAH medical college and hospital surendranagar. Result: In this study, out of 50 PLWHA patients, one infant was infected, 20% of them were breastfed, 36% were delivered by caesarean section, 56% were delivered by vaginal delivery, 8% were instrumental (6% vaccum assisted and 2% forceps delivery). Among them all mothers and infants were given treatment. Conclusion: Nevirapine has been shown to reduce significantly vertical transmission when it used antepartum and intrapartum by the mother and postpartum by the newborn for 6 weeks. The use of elective Caesarean section should probably be reserved for women who fail to achieve viral suppression at the time of delivery or if any obstetrical reasons in india. Breastfeeding reducesthe long-term efficacy of perinatal antiretroviral therapy. All PLWH patients should avoid breastfeeding the newborn if possible.