Role of prophylactic antibiotics in clean and clean contaminated operations-hospital based cross sectional study

Introduction: Prophylactic administration of antibiotics can be used to avoid surgical site infections, which are the primary cause of morbidity and mortality in patients. In spite of modern standards of preoperative preparation and refinements in anaesthetic and operative techniques, postoperative wound infections remain a serious problem. Objective: • To evaluate the incidence of surgical site infections following clean and clean contaminated operations. • To identify the common organisms detected in above scenario. • To identify the risk factors for postoperative wound infections. • To study the clinical profile of patients with clean and clean contaminatedoperation scenario. Methods: It is a hospital based cross sectional study of 200 patients tertiary care hospital over a period of one year and seven months from June 2015 to December 2016.Risk factors and post-operative wound infection rate was analyzed. Results: Out of 200 cases 14 cases got infected in both clean 12 (6.6%) patients and clean-contaminated 2 (11.11%) patients. In our study, out of 14 cases, infected 4 patients had no associated risk factors. Conclusion: Single dose of Cephalosporins can be used in clean operations and single dose of Cephalosporins and Metronidazole can be used for clean contaminated operations.