
There are many factors that influence the success of production of silk. In recent years, some antibiotic agents have been used for growth enhancement of silkworm larvae and improvement of silk production. This study regarding the effect of amoxicillin was conducted on the silkworm breed selected for the experiment was popular Indian bivoltine hybrid (CSR2XCSR4). The silkworm larvae were reared up to fifth instar without any treatment. Later the amoxicillin antibiotic solution was diluted by different concentrations (1%, 3% and 5%), each concentration were sprayed on the MR2 Mulberry (Morus sinensis) leaves. It was fed by silkworm larvae, III, IV and V instar. Group “C” larvae received MR2 mulberry leaves sprayed with distilled water, it was served as control. Groups T1, T2 and T3 larvae received 1%, 3% and 5% antibiotic solution sprayed mulberry leaves, respectively. In this groups, the T3 (5% concentration) was significantly increased the larval, pupal and cocoon parameters (length, width and weight) and economic parameters like cocooning percentage, shell weight, shell ratio, silk filament length, and denier of silk filament.