CALL FOR PAPERS

CERTIFICATE

IMPACT FACTOR 2018

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

Study of copper, zinc and cerruloplasmin albumin ratio in pulmonary tuberculosis patients on different drug regimes

Author: 
Dr. Sandhya Mishra, Pallavi Taparia, Dr. Dharamveer Yadav, Dr. Suresh Koolwal and Tapas Kanu Vyas
Subject Area: 
Life Sciences
Abstract: 

Introduction: Pulmonary Tuberculosis (PTB) is a severe bacterial infection that continues to be the main cause of morbidity and mortality. Compromised immune status due to micronutrient deficiency is one of the key factors predisposing to PTB infection. The aim of the present study was to assess the trace elements Copper and Zinc status in PTB patients and to evaluate the diagnostic role of Cerruloplasmin (Cp) and Cerruloplasmin Albumin ratio (Cp/Alb). Method: 120 Adult PTB patients (60 newly diagnosed and 60 relapse) attending the Institute of Respiratory Disease, SMS Medical College, Jaipur and 60 healthy non family members of patients / Controls were enrolled for the study. After informed consent, sputum examination and Routine Biochemical analysis along with Serum Copper (Cu), Zinc (Zn) and Cerruloplasmin (Cp) were estimated in fasting sample for all subjects. Result and Discussion: Serum Protein, Albumin and Zinc were significantly reduced in PTB group as compared to controls due to increased catabolism, anorexia, pre-existing undernutrition and Acute Phase Response associated with PTB. Serum Cu and Cp were significantly high which may be due to increased hepatic synthesis of acute phase proteins. Cu correlated strongly only to Cu/Zn ratio but the later was found to have good correlation with all parameters estimated. Similarly, Cp/Alb ratio correlates well with Cp as well as Cu and Zinc. Conclusion: Trace elements alteration in PTB is significant and can be used in nutritional monitoring of patients. Early estimation of micronutrient status can help identify at risk individuals and prevent occurrence of relapse. This would also enhance survival and early recovery of patients. Cp/Alb ratio can be used as additional tool to assist diagnosis and Prognosis of PTB.

PDF file: 

IJMCE RECOMMENDATION

ONLINE PAYPAL PAYMENT

CURRENT ISSUE

NEWS

CHIEF EDITOR
Rosane Cavalcante Fragoso, Brasil
ASSOCIATE CHIEF EDITOR

   

Jean-Marc SABATIER
Chief Scientific Officer and Head of a Research Group
France

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

EDITORIAL BOARD

Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran