
A cross-sectional study of dermatophilosis was undertaken from December 2016 to February 2017 on 770 cattle (693 local and 77 cross) with the aim of determining prevalence and associated risk factors in and around Horro guduru animal production and research center of wollega university, Horro guduru zone, western Ethiopia. Culturing of D.congolensis and Giemsa staining were the techniques used. Twenty eight of 770 examined animals (3.63%) had dermatophilosis. Prevalence was higher in indigenous zebu (2.83%) than in cross bred (0.94%) cattle, in female cattle (2.43 %) than in male (1.35%), in > 3 years old than in< 3 years old, in wet (2.02%) than in dry season (1.75%), and in cattle with no tick infestation (1.62%) than in cattle infested with tick (2.16%). Statistically significant difference (p<0.05) was observed in breed of cattle, age, season of the year and tick infestation (p<0.05). The study indicated dermatophilosis is a potential determinant factor for the dairy development. Therefore, factors that bring mechanical injury to the skin and management practices that promote transmission should be avoided.