
Introduction: Coronary artery disease is one of the major causes of death in young athletes all over the world, leading to sudden cardiac arrest. Knowledge of the coronary arteries along with its septal branches is very important. Interventional cardiologists treat these conditions by approaching the specific interventricular septal branches of the coronary arteries. Objectives: To study the septal branches of the interventricular septum arising from both the coronary arteries and their variations. Materials and method: This study was conducted on 50 specimens. The lumen of the coronary arteries were injected with cast material and made like thick scaffoldings then dissected under water and the variations were studied. Results: 64% were right dominant, 16% left dominant and 20% co-dominant. The branches to the interventricular septum were maximum in case of co-dominance. Discussion: In Hypertrophic cardiomyopathy, the volume of the left ventricle reduces gradually and decreases cardiac output. This condition can be treated by approaching the interventricular septum through the septal branches and causing local necrosis of the septum using alcohol. Conclusion: This study helps the interventional cardiologists to plan the line of treatment in Hypertrophic cardiomyopathy and ablate the septum using alcohol.