
Introduction: Fracture of Humerus shaft in adults can be managed conservatively with braces or operatively with plates or with intramedullary nails. Humerus intramedullary nailing is done either using humerus interlocking nails or Enders nails. In this study we analyse the outcome of humerus shaft fractures (upper and middle third) managed with closed antegradeintramedullary titanium elastic nailing in terms ofunion rates, union time, functional results and complications. Materials and Methods: A retrospective study of 25patients treated with ante-grade intramedullary titaniumelastic nailing was done during the period of january 2016 toJanuary 2018 at our tertiary care centre. Skeletally maturepatients with closed and acute fractures of the upper andmiddle shaft humerus of both sexes were included in thestudy. Results: Twenty-five (100%) fractures united with anaverage consolidation time of 14.98 weeks (10-32 weeks), and no fractures had non-union. Nail impingement wasseen in two (8%), shoulder stiffness in one (4%). Functionalresults were excellent in 22 (88%), moderate in two (8%) andpoor in one (4%). There were 17 males and eight femaleswith an average age of 39.08 years (range: 18-65 years). Theaverage duration of hospital stay was 3.84±2.30 days. Conclusion: Closed ante-grade intramedullary titaniumelastic nailing offers a safe and reliable method of fixingfractures of upper humeral shaft in adults. This methodprovides early fracture union, high union rates and lesscomplications, in addition to early rehabilitation and reducesthe hospital stay.