
Azima tetracantha Lam., (Salvadoraceae), is widely used in folklore herbal medicine practices in the villages of southern Kerala. The plant is claimed to have anti-inflammatory, antiperiodic, analgesic and wound healing properties. The present study evaluated the antimicrobial and antioxidant activity of A. tetracantha leaves. Methanolic extract showed greater antimicrobial activity than the chloroform extract. The extracts showed both the radical scavenging activity and reducing capability to fight against free radicals. The results from antimicrobial and radical scavenging assays of A.tetracantha leaves showed significant medicinal properties.