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“Edible” vaccine-vegetables as alternative to needles

Author: 
Ajaz Malik, Vashisht, V.K., Rizwan Rashid, Susheel Sharma and Jaskanwal Singh
Subject Area: 
Life Sciences
Abstract: 

Edible vaccines or Food Vaccine hold great promise as an easy-to-administer, cost-effective, easy-to-store, and socio-culturally willingly acceptable vaccine delivery for the developing countries. Edible vaccines offer exciting opportunities for significantly reducing the burden of diseases like hepatitis, cholera & measles, mainly in the developing world where the administrating & storage of vaccines is at major concern. The search for methods of vaccine delivery not requiring a needle and syringe has been accelerated by recent concerns regarding pandemic disease, bioterrorism, and disease eradication campaigns. Needle‐free vaccine delivery could aid in these mass vaccinations by increasing ease and speed of delivery, and by offering improved safety and compliance, decreasing costs, and reducing pain associated with vaccinations. Edible Vaccines are prepared by molecular farming with the help of genetic engineering. Preparation of Edible Vaccines are involving the introduction of selected desired genes into plants and inducing these genetically modified plants to manufacture the encoded proteins. This process is known as transformation and the altered plants are called transgenic plants. The vaccine is administered through the consumption of the edible plant as food, preferably in the form of a fruit or vegetable juice which can be taken orally.

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