“Impact of Follicular Fluid Anti-Mullerian Hormone Level on Follicular reserve, oocyte and embryo quality, fertilisation and pregnancy

Objectives: The purpose of this study is to investigate the relationship between the FF (AMH) levels and quality of oocyte and embryo, fertilisation and pregnancy. The process of in vitro fertilization depends on many factors.The failure of oocyte morphological assessment to predict in vitro fertilization (IVF) outcome has led the researchers to examine biochemical criteria of follicular fluid (FF). Anti-Mullerian hormone (AMH), an important marker of ovarian reserve, is secreted by the granulosa cells. Materials and Methods: The FF (AMH) levels of 60 patients (mean age: 33.72 ± 4.82 years; range: 21 to 42 years) were analyzed. The FF (AMH) levels were measured by the quantitative auto-analyzer with an electro-chemiluminescence assay. Results: The FF (AMH) levels in patients under 35 years of age were higher in pregnant women than non-pregnant ones (P<0.01).Conclusion: Our study results showed that the FF (AMH) levels were correlated with the quality of oocyte and embryo and were the predictors of clinical pregnancy in patients younger than 35 years of age.