In Senegal, the Angiosperms represent the best known and most diverse group. The main objective of this work is to contribute to a better knowledge of the biodiversity of Senegal. More specifically, this work seeks to analyse the diversity of Angiosperms in Senegal. The application of several sources of information (herbaria, floras and botanical gardens) has made it possible to show that the flora of Senegal is composed of 2512 species and 1006 genera distributed in 167 families. Dicotyledons are largely dominant with 1788 species distributed in 776 genera and 130 families. On the other hand, only 724 species of Monocotyledons distributed in 230 genera and 37 families have been recorded. The most representative families of Dicotyledons are the Fabaceae, Asteraceae, Apocynaceae, Rubiaceae, Malvaceae and Euphorbiaceae . These 6 families include 317 genera, i.e. 40.84% and 839 species, i.e. 46.93% of the Dicotyledonous flora of Senegal. For the Monocotyledons, they are mostly represented by the family Poaceae, Cyperaceae, Arecaceae, Araceae, Orchidaceae, Liliaceae, Commelinaceae. These 5 families account for 65.65% of the genera and 75.41% of the species of the Monocotyledonous flora of Senegal.