The methanol extract of Brassica oleracea var. capitata rubra was investigated for anti-inflammatory and antipyretic activity in animal models. The extract has an anti-inflammatory effect against paw oedema in rats. Brewer’s yeast (15%) suspension was used to induce fever in rats. Our results were P˂ 0.05 significant even at lower dosage of 0.50 mg/kg which showed the dominant nature of methanolic extract of Brassica oleracea var capitata rubra.