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The antifungal properties of some medical plants extracts

Author: 
Karkaz M. Thalij and Funda K. Guler
Subject Area: 
Life Sciences
Abstract: 

The antifungal activity of Alcoholic Medical Extracts (AMPE) of Leaf Thyme, Thymus mastichina L. Lamiaceae (AMPE-1); Leaf Rosemary, Rosmarinus officinalis L., Lamiaceae (AMPE-2); Cloves, Eugenia caryophyllus (AMPE-3); Bark, Cinnamomum zeylanicum (AMPE-4) and Roots Ginger, Zingiber officinale L. Zingiberaceae (AMPE-5), on fungal species suchas Aspergillus flavus, A.niger and A.ochraceuswere evaluated by a standard disc diffusion method after determining the activated agents in each medical plants. Besides, the effects of each AMPE on the ability of each fungal on mycotoxins producing were estimated. The results showed that AMPE contained the most activated agentssuch as Flavonoids, Polyphenols, phenolic glycosides, tannins, alkaloids, saponins and cyanogenic glycosides compounds that’s assessed. The minimum inhibition concentrations for each of AMPE against Aspergillus flavus, A.niger and A.ochraceus showed an inhibitory activation at 25 mg/ml in some AMPE .The inhibition activity was found to increase with the higher concentrations of other serial concentrations. The values of 25, 50 and 100 mg/ml from each AMPE antifungals activity revealed by the standard disc diffusion method showed that the inhibition activity were significantly (p<0.05) increased with the increased of each AMPE concentration. The concentration of 100 mg from each AMPE types was found to have an inhibitory activation at a range between 12 to 19 mm for the fungal strains. The results of the AMPE type's effects on mycotoxins produced from the fungal strains revealed that AMPE-1 and AMPE-2 at a concentration of 100 mg/ml increased significantly the Aflatoxin B1 and ochratoxin A production while other concentrations of AMPE types decreased significantly mycotoxins productions.

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