Apo-a1 levels in diabetes mellitus with or without cad

Study background: There is an increased incidence of Type-II Diabetes and Coronary artery disease (CAD) in the Indian subcontinent during the past few decades.1 Abnormalities in the Lipid profile considered to be atherogenic include hypertriglyceridemia, low HDL-Lipoprotein and hypercholesterolemia. Recently sub-fractions of the Lipoproteins are found to be predictive of CAD especially in type-II Diabetic patients. Aim of study: The present study consists of estimating Apo-A1 lipoprotein levels in Diabetic patients with CAD and without CAD. Study type: comparative study. Study sample: includes 60 type-II Diabetes patients with or without CAD from King George Hospital, Visakhapatnam. Result of study: Apo-A1 levels are found to be significantly lower in type-II Diabetes patients than normal controls. Apo-A1 levels are also lower in those with CAD than those without CAD in type –II Diabetes patients.