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Application of MR diffusion weighted imaging ADC in liver cirrhosis in the North-East China population

Author: 
Lkhagvadorj Tsendjav, Zhang Jian, Raihan Kibria and Zhang Lu
Subject Area: 
Health Sciences
Abstract: 

Objective: To investigate the diagnostic value of DWI (diffusion-weighted imaging) value of ADC (apparent diffusion coefficient) in early diagnosis of liver cirrhosis. Methods: From 2015 October to 2016 June this study investigated in 60 patients underwent diffusion-weighted imaging (DWI) with 3.0-T MRI, 30 liver cirrhosis patients and 30 healthy controls (control group). DWI was performed with b values of 0 s/mm2, 500 s/mm2 and 800 s/mm2. ADCs of liver were measured using in the right posterior lobe, right anterior lobe and left lobes of the liver. The data was entered into the computer and analyzed using the Statistical Package for Social Sciences (version 20.Inc. Chicago, USA) for analysis ADC value. Result: The ADC mean values of two groups had significant differences cirrhotic group b=500 s/mm2 mean value is 1.27 .b=800 s/mm2 mean value is 1.26, control group b=500 s/mm2 mean value is 1.33 0. b=800 s/mm2mean value is1.5. ADCs liver cirrhosis lower than control group. Conclusion: DWI at 3.0 T magnetic resonance in examination of liver could synthetically and quantitatively analyze the rule of ADC values in liver cirrhosis

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