Objective: To study the antibiotic prescribing pattern in surgery department of a tertiary care teaching hospital. Methods: A prospective observational study was conducted over a period of six months in a tertiary care teaching hospital. A total of 300 case records of inpatient undergone treatment in surgery department was reviewed. The relevant information was recorded in structured proforma and data was evaluated. Results: Case records of 300patients who have undergone surgery were observed during the study period. Antibiotics were recommended for 254 patients. The most preferred route of administration wereparenteral (95.27%) than oral route (3.94%) followed by both (0.79%). Cefotaxim was mostly prescribed (23.33%) followed by sulbactum (18.24%) and metronidazole (17.55%). Majority of prescriptions were prescribed with 2 antibiotics (53.15%) and single antibiotic was prescribed in 39.37% cases. Among the 154 antibiotic combination prescribed, out of which cefaperazone + sulbactum (39.61%) was the most commonly prescribed regimen followed by ciprofloxacin + metronidazole (8.87%) and Cefotaxime + metronidazole 27 (17.53%) . The first dose of antibiotic was administered more than 2 hour before operation in 143 (56.30%) cases. Conclusion: We have evaluated the prescribing pattern of antibiotics in Surgery department. Almost prescribing patterns were found to be rational, as we can see adherence to American Society of Health-System Pharmacists (ASHP) guidelines in many of the cases. The results of this practice can help to provide evidence for recommendations that may help to improve health care.
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