Assessment for the efficacy of various remineralising agents during fixed orthodontic mechanotherapy: in vivo studY

Introduction: Topical agents GC Tooth Mousse and Toothmin toothpaste show promise in their ability to prevent enamel demineralization during orthodontic treatment, however clinical data comparing the efficacy of these remineralizing is lacking. Therefore, the purpose of this in – vivo study was to investigate the efficacy of remineralizing agents available commercially which claim to reduce demineralization when applied topically adjacent to orthodontic brackets. Materials and Methods: The total study sample comprised of sixty sound premolar teeth from thirty subjects that will undergo fixed orthodontic mechanotherapy involving extraction. Data collected by scoring of the SEM images. The clinical scanning electron microscope study includes comparison of individual right side (subgroup a) and left side (subgroup b) Group (Control Group) along with overall comparison of statistics with each other (Group 1 and Group 2). Results: It was observed that the topical application of GC Tooth Mousse , Group 1 subgroup a and Toothmin toothpaste, Group 2 subgroup a was associated with a significantly statistical variation in the reduction of mean surface roughness when compared with the control Group 1 subgroup b , Group 2 subgroup b samples indicating that both GC Tooth Mousse and Toothmin toothpaste can be used by the orthodontic patients as a remineralising agent for the prevention of development of white spot lesions. Conclusion: The ability of Toothmin toothpaste in preventing demineralization was similar to that of GC Tooth Mousse. Topical application of the remineralizing agents – GC Tooth Mousse and Toothmin toothpaste was effective in preventing enamel demineralization.