CALL FOR PAPERS

CERTIFICATE

IMPACT FACTOR 2018

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

Assessment of fluoride status in patients with hypothyroidism

Author: 
Dr. Manju Bala Pahwa, Dr. Parveen, Dr. Rajesh Rajput and Dr. Meenakshi
Subject Area: 
Life Sciences
Abstract: 

Introduction: Fluorosis an endemic problem affects many tissues including endocrine glands such as thyroid. Iodine deficiency remains the most common cause of primary hypothyroidism worldwide. Fluoride and iodine are both halogens. Fluoride, the negative ion of the element fluorine, easily displaces iodine in the body because it is much lighter and therefore more reactive. Few studies have reported no relationship between serum fluoride levels and thyroid disorders, while others have reported decreased serum thyroid hormone levels are associated with increased fluoride levels in hypothyroidism. Goiter and hypothyroidism are known to be caused by iodine deficiency. However, it has also been found to occur in areas where there are adequate supplies of iodine, but where there is an excess fluoride in the water. The present study was conducted to assess the fluoride status in newly diagnosed cases of hypothyroidism. Aims & objectives 1) To assess the fluoride status in the patients of hypothyroidism and healthy controls. 2) To correlate the fluoride status with the severity of hypothyroidism. Material & Methods: The present study was conducted in the Department of Biochemistry in collaboration with Department of Medicine (Endocrinology), Pt. B.D. Sharma PGIMS, Rohtak. Fifty newly diagnosed patients with hypothyroidism in the age group 20-55 years and fifty age and sex matched healthy controls were taken in the study. Fasting venous blood samples were collected from cases and controls for routine biochemical, hormone analysis and fluoride estimation after obtaining informed written consent and complete history. Results: Mean water fluoride level of cases was 2.308 ± 0.282 ppm (Mean ± SE) and of controls was 1.659 ± 0.183 ppm and found to be statistically significant. Mean value of serum fluoride levels in study group was 0.234 ± 0.023ppm and of controls was 0.058 ± 0.007ppm and found to be statistically significant. Mean urine fluoride level of cases was 2.359 ± 0.146 ppm and of controls was 1.577 ± 0.166 ppm and found to be statistically significant. TSH in the study group (20.924 ± 2.398) and control group (2.817 ± 0.186) were compared and found to be statistically significant. Discussion & Conclusion- In the present study the serum & urinary fluoride levels in the study & control groups indicate the likelihood of fluoride ingestion from food & other sources is apparently, like dental products, cosmetics etc. It is evident in consistent with the findings of reported studies that analysis of fluoride in body fluids besides drinking water is highly relevant & necessary for understanding & prevention of potential health implications like hypothyroidism seen in endemic areas.

PDF file: 

IJMCE RECOMMENDATION

ONLINE PAYPAL PAYMENT

CURRENT ISSUE

NEWS

CHIEF EDITOR
Rosane Cavalcante Fragoso, Brasil
ASSOCIATE CHIEF EDITOR

   

Jean-Marc SABATIER
Chief Scientific Officer and Head of a Research Group
France

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

EDITORIAL BOARD

Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran