Paddy this study aimed To investigate the possible relationship between anemia and oral hygiene and to evaluate the periodontal status of patients with anemia. A total of approximately (50) patients consisted of ….males and …. Females who have Anemia as systemic disease of any age group in saudi Arabian kingdom participated in the study, Our study showed strong relationship between anemia as systemic disease and periodontal problems, while there wasn’t relationship between anemia and oral hygiene.