Central odontogenic fibroma (COF) is extremely rare benign neoplasm which stands for less than 0.1% of odontogenic tumors. COF is mainly derived from dental origin tissue of mesenchyme-like dental papilla, periodontal ligament or dental follicle. It has more predilections in the mandible than in maxilla. Radiographically it shows both unilocular as well as a multilocular radiolucent lesion with a sclerotic border. Histologically it shows dense mature connective tissue stroma consisting of mature collagen fibers and plenty of fibroblasts which are usually plump and active in nature. COF is broadly of two types one is a simple type and other is WHO type. Here in our case, 09 years old girl represents central odontogenic fibroma in the mandible.
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