Case series of primary amenorrhoea

Background: Amenorrhoea is absence of menstrual bleeding . Primary Amenorrhoea is absence of menstruation and secondary sexual characters by age of 14 years or absence of menstruation regardless of secondary sexual characters by age of 16 years. For a normal menstruation to occur the normal genetic makeup, neuro-endocrinological, embryological development is must. Any abnormality in above leads to amenorrhea. Incidence of Primary Amenorrhea is less than 1%. Objective: The objective of this study was to note the various causes, complete clinical picture and the management in 25 such cases of Primary Amenorrhoea. Materials and Methods: This is a Prospective study done in 25 cases .They were thoroughly investigated (i/e clinical examination,radiological examination and hormonal study) to get the exact cause of Primary Amenorrhoea. Results: Out of 25 cases studied, maximum cases presented at 14-16 years of age, with chief complaint of primary amenorrhoea, out of which 8% of them were married, 44% cases were of MRKH (Mayer-Rokitansky-Kuster-Hauser syndrome) which was the most common cause of Primary Amenorrhoea in our study. Conclusion: Most common cause of primary amenorrhoea in our study was MRKH Mayer-Rokitansky-Kuster-Hauser syndrome with normal secondary sexual characterstics.