Mixed dentition is the most crucial period because early treatment would correct the occlusion as well as ensure normal development of teeth and jaws. Interceptive procedures not only simplify but also eliminate the need for the later treatment procedures. A most important advantage of early interception is that the majority of the malocclusion can be corrected non surgically and without the extraction of permanent teeth. This article presents three cases of correction of malposed teeth in the mixed dentition period using a 2x4 appliance.