CALL FOR PAPERS

CERTIFICATE

IMPACT FACTOR 2019

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

 

 

 

 

 

 

 

 

 

 

 

Characterization of skeletal metastases of known and unknown origins

Author: 
Kerilyn N. Godbe, BS, Alyssa N. Wenzel, BS, Zainab Ibrahim, MD, Airi Katoh, MD, 1Cynthia Morrow, MD and Douglas J. Grider, MD
Subject Area: 
Health Sciences
Abstract: 

Background: There are limited epidemiologic studies characterizing skeletal metastasis, and fewer, if any, that comprehensively compare and contrast patients who are initially diagnosed with skeletal metastases of unknown primary (SMUP) to patients who have a known primary at the time that skeletal metastases are identified. Methods: This single-centered retrospective study provides a descriptive analysis of patient characteristics (demographics including but not limited to sex, age, and history of tobacco use), lesion characteristics (sites of primary lesion as well as number and location of metastatic lesions), and outcomes for patients identified as having SMUP compared to patients with a known primary cancer who have skeletal metastases. Results: In this study, 164 patients were identified as having bone metastases through record review of ICD-9 and ICD-10 codes. Of these patients, 65.9% had a known primary prior to identification of bone metastases while 34.1%were classified as having SMUP. Patients identified with SMUP were disproportionately male while patients with a known primary were disproportionately female. No other significant differences were identified for other patient characteristics. For patients with bone metastases with known primaries, the most common primary sites were lung, breast, and prostate carcinoma, in that order. However, the most common primary sites for patients with SMUP were, in order, lung, prostate, and breast carcinoma. The most common location for metastases, regardless of known or unknown primary was the spine, followed by the pelvis and the ribs. Lastly, with respect to long term prognosis, while there was a significant difference in patients’ survival time based on solely on SMUP status, there was no difference in survival once bone metastases were identified, regardless of whether the primary is known, as all bone metastases carried a poor prognosis. Conclusion: There are significant differences in the male to female ratio with respect to the initial presentation of bone metastases when comparing known primary to unknown primary malignancies. SMUP are more common in males than females, with 61% of males initially presenting with SMUP compared to only 39% of females presenting with SMUP. This finding warrants further evaluation of the etiology of this difference, which may potentially be clinically significant.

PDF file: 

IJMCE RECOMMENDATION

ONLINE PAYPAL PAYMENT

CURRENT ISSUE

NEWS

CHIEF EDITOR
Rosane Cavalcante Fragoso, Brasil
ASSOCIATE CHIEF EDITOR

   

Jean-Marc SABATIER
Chief Scientific Officer and Head of a Research Group
France

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

 

 

 

 

 

 

 

 

 

 

 

EDITORIAL BOARD

Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran