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Cleidocranial Dysplasia: A case report

Author: 
Ashwini Jangamashetti, Siddesh Shenoy, Krishnakumar, R. and Husna Patel
Subject Area: 
Health Sciences
Abstract: 

Cleidocranial dysplasia is a rare congenital disease. It is characterized by autosomal dominant inheritance pattern with equal sex distribution which is caused due to mutations in the Cbfa1 gene (Runx2) located on chromosome 6p21. It primarily affecting skull, jaws, teeth, clavicle along with other skeletal abnormalities. It presents with skeletal defects of several bones, like partial or complete absence of clavicles, late closure of the fontanels, presence of open skull sutures and multiple wormian bones. This rare syndrome is of utmost importance in dentistry due to presence of multiple supernumerary teeth, facial bones deformities and deranged eruption patterns .We are reporting a classical case of cleidocranial dysplasia in 12 year old patient.

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