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Clinical pathological characteristics and 1- year survival of gastric cancer patients attending ocean road cancer institute, Tanzania

Author: 
Halima Sultan Mlandula MBBS, MMed, Crispin Kahesa MD, Msc, PhD and Nazima Dharsee MD, MMed, Msc,
Subject Area: 
Health Sciences
Abstract: 

Background: Gastric cancer is one of the most common cancer worldwide and the second most common cause of death after lung cancer (6).GLOBOCAN recent (2018) estimate had shown that in Tanzania, the incidence of the new cases was 1353(3.2%) in both male and female which ranks 7th as well as 6th in terms of death, which accounts for almost 1323(4.6%) of all cancer cases diagnosed annually. Aim of this study was to determine the clinical-pathological characteristic and 1-year survival in gastric cancer patients at Ocean Road Cancer Institute, Tanzania. Methodology: This study was conducted in September 2021,retrospective hospital-based study that analyzed the medical records of patients diagnosed with gastric cancer at Ocean Road Cancer Institute from 2013 to 2017.Data extraction forms were used to extract information from files and analysis was be done by using SSPS version 23. Result: Among 150 documented cases of gastric cancer during this period 101(67.3%) were male and 49(32.7%) female., The most frequent presenting symptoms were abdominal pain followed by weight loss; the most common histopathology was adenocarcinoma, and the majority of patients presented with advanced disease stage III and IV (87.3%).Survival is good to those who treated with surgery and chemotherapy, Partial gastrectomy as better survival than total gastrectomy, and other chemotherapy regimens as better survival than capecitabine alone. Conclusion: The majority of our patients of gastric cancer were diagnosed at an advanced stage, the male and female were 2.4:1, common histopathology was adenocarcinomas. The study revealed that gastric cancer has a poor prognosis with a 1-year survival of 18.7%.

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