Dental implants have become a predictable treatment option for restoring missing teeth. The successful outcome of any implant procedure depends on a series of patient related and procedure dependent parameters. Bone density has been suggested as one of the main factors influencing implant therapy success. Purpose: To compare the bone densities of maxillary and mandibular bones in pre and post-menopausal women. Methods: Data was obtained from cone beam computed tomography of 2 groups: 20 premenopausal women and 20 post-menopausal women. Bone density was measured in maxillary and mandibular posterior region using the CS 3D software. Group averages were calculated and compared. Results: a significant difference was found in the bone densities of 2 groups (p< 0.0001). Bone density of maxilla and mandible in post-menopausal women was less compared to pre-menopausal women. Conclusion: The bone density of post-menopausal women is less as compared to pre-menopausal women. Radiographic analysis of the bone using CBCT is recommended to plan ahead for the consequences and complications, which can arise later.