The aim of the present work is to evaluate and compare experimental toothpaste with commercial toothpastes. In the study, commercial toothpastes such as colgate, close up and pepsodent have been used and also can be evaluation studies were performed for their quality. All the marketed tooth pastes and experimental toothpaste which had been evaluated the complied with the standards specified by the Bureau of Indian Standards. The formulations were subjected to various evolution tests like pH, spreadability, abrasiveness, fineness, foaming ability, cleaning ability, moisture and volatile content, F, Pb, As, tube inertness and stability studies. All the Results of evaluated parameters showed that experimental formulation is comparably equal and rarely better in terms of results than marketed formulation. Hence, the selected experimental formulation was found to be of good quality.