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To compare performance of risk of malignancy index 2, 3 and 4 in preoperative discrimination between benign and malignant ovarian tumours

Author: 
Dr. Sunita Singhal, Dr. Premlata Mital, Dr. Richi Ainani, Dr. Alka Batar, Dr. Priya Sonkhya, Dr. Renu Jain, Dr. Monika Agarwal, Dr. Aditi Gupta, Dr. Kavita Chaudhary and Dr. UrmilaKharbas
Subject Area: 
Health Sciences
Abstract: 

Ovarian tumours commonly present as adnexal masses which could be benign or malignant. To predict nature of ovarian tumours preoperatively is a great challenge for the gynaecologists preoperatively because of their bizarre and atypical behaviour. The present study was done to compare performance of Risk of malignancy Index 2, 3 and 4 in preoperative discrimination between benign and malignant ovarian tumours. Methods: 175 women with ovarian tumours were included after obtaining informed written consent in the study. Risk of malignancy index 2,3 and 4 were calculated by their respective formulas using USG score, menopausal score and serum CA 125 level. Performance of these three indices were compared. Results: The sensitivity of RMI 2, RMI 3 and RMI 4 was 58.06%, 54.84% and 61.3% respectively. The specificity of RMI 2, RMI 3 and RMI 4 was 98.61%, 98.61% and 99.31% respectively. The positive predictive value and negative predictive value of RMI 4 were more than RMI 2 and RMI 3. Diagnostic accuracy of RMI 4 was 92.6% and that of RMI 2 and RMI 3 were 91.43% and 90.86% respectively. There was no significant difference in the performance of these three indices (p-.98) Conclusion: RMI is a simple, cost effective and easily applicable method to evaluate nature of ovarian tumours preoperatively. RMI 4 is slightly better than RMI 2 and RMI 3 in our study.

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