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Comparison of efficacy of different diagnostic modalities of lung cancer: bronchoscopic methods (bal, tbna, eblb), ct-fnac, pleural fluid (aspiration cytology, pleural biopsy), lymph node fnac

Author: 
Kapil Sharma, Vishal Patidar, Avinash Jain, Sheena Taneja, Sudan, D. P. S., Monica Sharma and Mishra, J. K
Subject Area: 
Health Sciences
Abstract: 

Background: Bronchogenic carcinoma usually has fatal consequences but early diagnosis remains a challenge in developing nation like India. Bronchoscopic methods and CT guided FNAC are valuable tools for early diagnosis of both central and peripheral lesions. Objectives: To compare the diagnostic efficacy of Bronchoscopic methods (BAL, TBNA), Pleural Fluid (aspiration cytology, pleural biopsy), Lymph node FNAC while considering CT-FNAC of lung masses and EBLB as Gold Standard tests. Materials and Methods: Study was carried out for more than 4 years and various modalities of lung cancer were offered for CT diagnosed cases of lung masses. Data of 198 cases was recorded for statistical analyses. Results: Study obtained higher sensitivity of BAL samples and Lymph node FNAC as 79.17% and 88.2 % respectively. However, there was low sensitivity of pleural fluid cytology and pleural biopsy as 26.4% and 11.11% respectively. The study recorded good specificity and accuracy for all the modalities. Conclusion: We conclude to perform CT guided FNAC of masses, Bronchoscopic methods and lymph node FNAC for early detection of bronchogenic carcinoma.

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