
Background: Diabetes Mellitus and obesity are increasing in the population undergoing Coronary Artery Bypass Graft, and these conditions are major factors in the development of Metabolic Syndrome. Metabolic syndrome is a group of factors that associated with an increased cardiovascular risk. The purpose of this study was to determine postoperative morbidity and mortality in patients with metabolic syndrome compared to patients with metabolic syndrome who undrewent Coronary Artery Bypass Grafting (CABG) surgery at H. Adam Malik General Hospital Medan. Patients and Methods: This study is an analytical study with a cross-sectional design, by taking secondary data from the medical records of patients who underwent CABG at H. Adam Malik General Hospital Medan, with total of 74 patients. Analysis of the data was using the Chi-Square test, which must be obtained p <0.05, the difference is statistically significant. Results: From 74 patients, we found statistically significant difference (p <0.05) on duration of intubation, and post-CABG surgery wound infection, there were longer postoperative CABG stay and intubation in the patient groupwith the metabolic syndrome and higher number of patient with post surgery wound infection in the group of patients with the metabolic syndrome compared to the group without the metabolic syndrome. Conclusion: Duration of stay, duration of intubation, and minimalizing of surgical wound infection, especially in patients with metabolic syndrome contributed in postoperative morbidity of CABGsurgery.