
Introduction: Robotic guidance system is particularly useful in reaching and targeting complex lesions in critical or difficult to reach areas for CT guided procedures. Aims and Objectives: To perform a pilot study of CT guided biopsy using a new commercially available robotic guidance system on a group of challenging lesions. Methods and Materials: Six patients underwent the procedure using 18G coaxial biopsy needle, and ease, procedure time, radiation dose and success rates were evaluated by two operators. Results: The procedure was uneventful in all cases and patients were sent back home after about one hour post-procedure observation. Average DLP was 238.03 (47.5-552), and time of procedure was 37.5 min. (30-50 min.) including patient positioning, preparation, planning and the actual biopsy procedure. 100% was the sampling rate and success result. Conclusion: Robotic guidance system offers ease of usage with low radiation dose and good procedure success rates.