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Dermatofibrosacoma protuberans: an experience of 10 cases & review of literature

Author: 
Dr. Sanjay Kumar Bhasin, Dr. Sunita Kumari, Dr. Ankit Gupta and Dr. Gopal Sharma
Subject Area: 
Health Sciences
Abstract: 

Dermato fibrosarcoma protuberans (DFSP) is considered to be a very rare, low-grade sarcoma of fibroblast origin from the Dermis of the skin. Controversy exists regarding its tissue origin. In present prospective study 10 patients in age group of 32-70 years, 07 females and 03 males all except 01 belonging to Hindu religion formed base of the data. Clinical examination, FNAC and histological study fetched the diagnosis. Majority of patients were having disease for the first time (n=07) and commonest site involved was shoulder, in 01 patient old scar was the site and in another 01 patient neck was the site of the disease. All the patients were subjected to wide local excision and in 02 patients radiotherapy was also given. Maximum follow up of our patients was 03 years (n=04). We conclude that DFSP is locally recurrent tumor having low metastatic potential. Wide surgical excision with 3 to 5 cm wide margins and MMS are surgical options, whereas, Imatinib and Radiotherapy is given in specific indications. Sorafenib trials are under way as good tumor regression response in few studies has been noticed.

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